Reductil (sibutramine hydrochloride) is a medicine intended for effective management of obesity. It must be combined with low-calorie diet and exercise for you to see the first effects soon and be able to maintain them. Reductil is usually well tolerated, especially when your body adjusts to the dosage prescribed. Until this happens, taking Reductil may be associated with a number of side effects such as increased blood pressure, headache, insomnia, increased heart rate, increased sweating, dry mouth, and constipation. You do not have to worry abut the side effects mentioned, as this drug is usually well tolerated and the symptoms listed above are most likely to go away on their own without any need for your doctor’s interference. Serious side effects need to be reported to your health care provider as soon as you first notice them. The following ones are sometimes reported: depression, disorientation, restlessness, abdominal pain, lightheadedness, irregular heart beats, vomiting, nausea, dilated pupils, shortness of breath, mental confusion, anxiety, high fever, nervousness, loss of muscle coordination, and sweating.